In the current study, we found that AML patients who were homozygous for the wild-type polymorphism of the MDR1 gene (A …
aacrjournals.orgAbstract Background: Acute myeloid leukemia (AML) shows substantial biological and clinical heterogeneity that extends beyond …
www.frontiersin.orgOur findings showed that the G2677 T and C3435 T polymorphisms of the MDR1 gene were associated with the age at onset of AML …
www.sciencedirect.comIn this case-control study, we examined the impact of C1236T MDR1 gene polymorphism on the risk of developing AML in 131 …
pmc.ncbi.nlm.nih.govMulti-omics analyses, such as single-cell transcriptomics, have revealed many potential new targets to improve AML prognosis from …
www.frontiersin.orgWe detected nine single nucleotide polymorphisms (SNPs) in immune checkpoint‐related genes, including PD1, LAG3, TIM3, and …
pmc.ncbi.nlm.nih.govAcute myeloid leukemia with complex karyotype (CK-AML) is associated with poor prognosis, which is only in part explained by …
ashpublications.orgIn summary, ATAC-based chromatin profiling, combined with multiomics data, provides insights into AML pathogenesis beyond …
www.nature.comOur findings suggest that immunorelated gene polymorphisms are associated with prognosis in AML, which may perform as novel …
onlinelibrary.wiley.comRecent updates in the WHO and ICC classifications have redefined AML-MRC, emphasizing molecular and cytogenetic criteria over …
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